Features Key features of the HTC One  vs iPhone 5c 

screen size

System font, for whatever reason, has been moved to the 'Accessibility' menu (it's still in display settings, too), which I highly suggest turning to 'small' if your eyes are any good.
HTC One | by Android Police (Apr, 2013)

screen resolution

HTC One
1920 x 1080
iPhone 5c
1136 x 640
Impressively, further image adjustments can be made using a row of +/- 2EV sliders for exposure, contrast, colour saturation and sharpness, which is more than most handsets offer 'smartphone photographers.
HTC One | by TechRadar (Mar, 2014)

memory

HTC One
2 GB
iPhone 5c
1 GB

processor

HTC One
Quad core
iPhone 5c
Dual core
Performance is flawless on the new Snapdragon 600 quad-core chip.
HTC One | by PhoneArena (Mar, 2013)

camera resolution

HTC One
13 MP
iPhone 5c
8 MP
Critics of the previous camera might be disappointed to find that this is the same UltraPixel sensor setup: it's still a 4-megapixel resolution and one of the side-effects of that is that the HTC One (M8) doesn't offer much scope to crop or digitally zoom like the Nokia Lumia 1020.
HTC One | by PocketLint (Apr, 2014)

Differences What are the advantages of each

View of HTC One

Reasons to consider the
HTC One

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Has expandable storage SD, SDHC, SDXC vs None Use storage cards to increase your phone's capacity for apps and data
Much longer talk time (3G) 1,608 min vs 600 min Around 2.8x longer talk time (3G); go days without charging
Much faster processor 2.3 GHz vs 1.3 GHz More than 75% faster processor; run computation-intensive applications, such as photo editing, faster
Supports NFC Yes vs No Somewhat common; Enables payment by phone and other wireless communications
Much higher resolution 1920 x 1080 vs 1136 x 640 More than 2.8x higher resolution
Significantly more battery capacity 2,600 mA·h vs 1,507 mA·h Around 75% more battery capacity
More cores Quad core vs Dual core Twice as many cores; each additional core lets your phone do more without visible UI slowdowns and jerkiness
Significantly sharper screen 440 ppi vs 325 ppi More than 35% sharper PPI; enjoy photo-realistic, crisp images
Noticeably bigger screen 5" vs 4" 25% bigger screen
Significantly higher resolution front camera 13 MP vs 8 MP Around 65% higher resolution front camera; Video chat with other people
More RAM 2 GB vs 1 GB 2x more RAM; browse media-heavy webpages without slowing down
Longer standby time (3G) 30,240 min vs 15,000 min More than 2x longer standby time (3G)
Back view of Apple iPhone 5c

Reasons to consider the
Apple iPhone 5c

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Acts as a wi-fi hotspot Yes vs No Somewhat common; Share your cellphone's data plan with other devices
Store more stuff 32 GB vs 16 GB 2x more storage capacity; free yourself from memory cards
Significantly better theoretical download speed 100 Mb/s vs 42.2 Mb/s More than 2.2x better theoretical download speed; enjoy lightning fast downloads on modern networks
Records higher def video 1920 x 1080 @ 30 fps vs 1920 x 1080 @ Unknown 30x higher def video
Lighter 132 g vs 145 g Around 10% lighter
Thinner 9 mm vs 9.9 mm Around 10% thinner

Reviews Word on the street

HTC One  vs iPhone 5c 

8.5
8.2
With a large, 5-inch, 1080 x 1920 pixel resolution IPS display, the One E8 is well-positioned to deliver a great user experience, as image reproduction is crisp thanks to those excellent 441 pixels per inch.
HTC One

10.0
8.0
The LCD display comes protected by Corning Gorilla Glass 3 and offers great viewing angles.
HTC One

9.5
8.0
Our daylight images would benefit from a tad more brightness and contrast for example, as would our interior still life shot likewise benefit from an application of the HTC's built-in filter in the Google Play version.
HTC One

Overall

9.0 Out of 10
7.9 Out of 10

Specifications Full list of technical specs

screen

HTC One  vs
iPhone 5c 
Size 5" 4"
Resolution 1920 x 1080 1136 x 640
Multitouch N/A Yes
PPI 440 ppi 325 ppi

hardware

Clock speed 2.3 GHz 1.3 GHz
Number of cores Quad core Dual core
RAM 2 GB 1 GB
Internal storage 16 GB 32 GB
Supported card formats
SDXC
SDHC
SD

photo & video

Camera 13 MP 8 MP
Resolution 13 MP 8 MP
Flash Yes Yes
Secondary camera 5 MP 1.2 MP
Video resolution 1920 x 1080 @ Unknown 1920 x 1080 @ 30 fps

cellular

Generation 4G 4G
Networks
LTE (20 Mb/s)
GPRS (0.01 Mb/s)
HSUPA (7.2 Mb/s)
UMTS (0.38 Mb/s)
EDGE (0.38 Mb/s)
LTE Cat3 (100 Mb/s)
LTE Cat 3 (100/)
HSDPA+ (42.2 Mb/s)
GSM (0.01 Mb/s)

battery

Talk time (3G) 1,608 min 600 min
Standby time (3G) 30,240 min 15,000 min
Capacity 2,600 mA·h 1,507 mA·h

form factor

HTC One  vs
iPhone 5c 
Weight 145 g 132 g
Thickness 9.9 mm 9 mm
Size 70.7 x 146.4 x 9.9 mm 59.2 x 124.4 x 9 mm

sensors

Has an assisted GPS Yes Yes

music

Supports FM radio No No

software

Operating system Android 4.4.2 iOS 7
Multitasking Yes Yes
App store Android Market Apple App Store
Adobe flash support No No
App store size 850,000 apps 825,000 apps

connectivity

Acts as a wi-fi hotspot No Yes
Supports NFC Yes No
Bluetooth Bluetooth v4.0 Bluetooth v4.0
HTC One
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Apple iPhone 5c
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